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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Astragalus polysaccharides attenuate rat aortic endothelial senescence via regulation of the SIRT-1/p53 signaling pathway

Fig. 5

Effect of APS on primary RAEC senescence. (a) Western blotting bands showing SIRT-1, p53, p21 and p16 expression in RAECs isolated from young and old rats treated with APS. (b-e) Relative intensities of SIRT-1, p53, p21 and p16 in young and senescent RAECs treated with APS. (f) Western blotting bands showing eNOS expression in each group. (g) Relative intensities of eNOS protein bands are shown. Values are the means ± S.D. (n = 6). * p < 0.05, ** p < 0.01 vs. old group; ## p < 0.01 vs. young group. Young: RAECs isolated from 2-month-old rat group; Old: RAECs isolated from 20-month-old rat group; APS: the RAECs isolated from 2-month-old rats treated with APS group; Old + APS: the RAECs isolated from 20-month-old rats treated with APS group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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