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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Astragalus polysaccharides attenuate rat aortic endothelial senescence via regulation of the SIRT-1/p53 signaling pathway

Fig. 2

Effect of APS on serum NO and eNOS levels, oxidative stress indicators and senescent aortic tissue in old rats. (a-e) NO and eNOS concentrations, CAT activity, and MDA and SIRT-1 levels in the serum of rats. Values are the means ± S.D. (n = 6). (f) Western blotting bands showing expression levels of aging-related proteins, including SIRT-1, p53, p21 and p16, in old rat aortic tissues treated with low to high doses of APS. (g) SIRT-1 activity in aortic tissue homogenate from old rats treated with low to high doses of APS. The results are presented as a percentage of control group (taken as 100%). (h-k) Relative intensities of SIRT-1, p53, p21 and p16 proteins are shown. Values are the means ± S.D. (n = 6). * p < 0.05, ** p < 0.01 vs. control group. Con: old rat group as control group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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