Table 7 Pharmacokinetic characteristics of active ingredients in TGT
| Â | Pharmacokinetics | |||||||
|---|---|---|---|---|---|---|---|---|
| Â | GI absorption | BBB permeant | P-gp substrate | CYP1A2 inhibitor | CYP2C19 inhibitor | CYP2C9 inhibitor | CYP2D6 inhibitor | CYP3A4 inhibitor |
Tenacigenin B | High | No | Yes | No | No | No | No | No |
Marsdekoiside | Low | No | Yes | No | No | No | No | No |
Taraxasterol | Low | No | No | No | No | No | No | No |
Tenacissoside G | Low | No | Yes | No | No | No | No | No |
Tenacissoside L | Low | No | Yes | No | No | No | No | No |
Tenacissoside J | Low | No | Yes | No | No | No | No | No |