Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma

Table 2 The fifty targets of TGT against osteosarcoma

Num	Target	Degree	Num	Target	Degree	Num	Target	Degree
1	EGFR	74	18	RAF1	26	35	CXCR1	14
2	VEGFA	70	19	TOP1	26	36	VDR	14
3	JUN	58	20	TYMS	26	37	POLA1	14
4	STAT3	56	21	MET	24	38	FOLH1	14
5	HSP90AA1	54	22	PRKCA	22	39	DPP4	12
6	ESR1	50	23	CYP19A1	22	40	POLD1	12
7	PTGS2	48	24	FLT1	20	41	KDM4C	10
8	AR	42	25	CXCR2	18	42	HMGCR	10
9	KDR	38	26	ESR2	18	43	HSD11B1	8
10	CDK1	36	27	AURKB	18	44	HSD11B2	8
11	FGF2	36	28	BRD4	18	45	MMP12	6
12	HDAC1	34	29	AURKA	18	46	PFKFB3	6
13	NR3C1	34	30	LGALS3	16	47	P2RY2	6
14	IL2	32	31	MMP8	16	48	NR1H3	6
15	MMP2	32	32	EIF4E	16	49	KDM2A	6
16	CREBBP	30	33	CDC25A	16	50	DTYMK	6
17	ABCB1	30	34	FGF1	14

ISSN: 2662-7671