Fig. 12From: Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcomaTGT regulates the expression of key target genes in osteosarcoma cells 143B and SAOS2. The concentration of TGT is 75 mg/mL. A JUN, (B) TYMS, (C) HSP90AA1, (D) HDAC1, (E) CDK1, (F) ESR1, (G) TOP1, (H) EGFR, (I) STAT3, (J) NR3C1, (K) VEGFA, (L) AR, (M) CREBBP, and (N) PTGS2. Data are presented as mean ± SD (n = 4).*P < 0.1, **P < 0.01, ***P < 0.001 and ****P < 0.0001 versus the Control groupBack to article page