Fig. 3

ALFF and DC values compared at different time points in 2 groups of patients. A Comparison of baseline ALFF values in various brain regions between patients with non-menstrual MWoA (Group 1) and healthy controls (Group 2). Increased ALFF values were observed in the left fusiform gyrus, while decreased ALFF values were observed in the right angular gyrus, left middle occipital gyrus, bilateral prefrontal cortex and left inferior parietal lobule. The brain regions with red-yellow color indicate a significantly increased ALFF value in Group 1 compared with Group 2, while the brain regions with green-blue color indicate a significantly decreased ALFF value in Group1 compared with Group 2 (P < 0.001; FDR corrected; Voxels > 60). B Comparison of brain regions with DC values at baseline between Group 1 and Group 2. Increased DC values were observed in bilateral fusiform gyrus, bilateral inferior temporal gyrus and right middle temporal gyrus. Decreased DC values were observed in right angular gyrus, right superior marginal gyrus, right inferior parietal lobule, right middle occipital gyrus, right superior frontal gyrus, right middle frontal gyrus, right anterior central gyrus and right complementary motor area. Brain regions with red-yellow color indicate a significantly increased DC value in Group 1 compared with Group 2, while brain regions with green-blue color indicate a significantly decreased DC value in Group1 compared with Group 2 (P < 0.001; FDR corrected; Voxels > 60). C Results in group 1: ALFF values of the right inferior temporal gyrus, right fusiform gyrus and right middle temporal gyrus after acupuncture significantly decreased compared with the time points before acupuncture (P < 0.001; FDR corrected; Voxels > 20). Brain regions with green-blue color indicate a significantly decreased ALFF value. D Results in group 1: DC values of the right inferior temporal gyrus, right fusiform gyrus and right middle temporal gyrus significantly decreased compared with the time points before acupuncture (P < 0.001; FDR corrected; Voxels > 20). Brain regions with green-blue color indicate a significantly decreased ALFF value