Fig. 5

In vitro validation of the network pharmacology analysis. A Cell viability of H460 and H1299 cell lines after SH003 treatment for 24 h was measured using the MTT assay. The data are shown as the means ± SEM, three individual experiments, *p < 0.05 compared to Control. B The representative western blot image of key targets in H460 and H1299 cell lines after SH003 treatments (C: Control, 0.1% DMSO; SH003: 100, 200, 400 μg/mL). Experiments were performed in triplicate