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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Baicalin enhances proliferation and reduces inflammatory-oxidative stress effect in H2O2-induced granulosa cells apoptosis via USP48 protein regulation

Fig. 5

USP48 knockdown reversed the inhibitory effect of BAI on oxidative stress and inflammation in H2O2-stimulated KGN cells. KGN cells in three groups were treated with 100 µmol/L H2O2 and 20 µmol/L BAI for 24 h. A ROS levels were measured by flow cytometry after siUSP48-1 transfection at 24 h. B The levels of MDA, GSH-PX, CAT, and SOD were measured after siUSP48-1 transfection at 24 h. C The levels of IL-1β, IL-6, IL-8, and TNF-α were measured by ELISA after siUSP48-1 transfection at 24 h. *p < 0.05

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