Fig. 4
USP48 knockdown inhibited the proliferation of H2O2-stimulated and BAI-treated KGN cells. A USP48 mRNA levels in KGN cells were measured by qRT-PCR after siUSP48 transfection for 24 h without H2O2 and BAI treatment. B and C The mRNA and protein levels of USP48 in H2O2-stimulated KGN cells in response to BAI treatment were measured by qRT-PCR and western blotting after transfection with siUSP48-1 and siUSP48-2 at 24 h. D The effect of USP48 knockdown on BAI-treated H2O2-induced KGN cell proliferation was analyzed using CCK8 after transfection at 24 h. E The effect of USP48 knockdown on apoptosis in BAI-treated H2O2-stimulated KGN cells was analyzed using an apoptosis kit after siUSP48-1 transfection at 24 h. *p < 0.05