Table 1 Effective mean concentration (EC₅₀) of Escallonia extracts on nontumor (HEK-293T), breast cancer (MCF-7), colon cancer (HT-29), and prostate cancer (PC-3) cell lines

E. illinita

Stem

D

44.0401 ± 2.8211^c

24.9665 ± 3.0838^c

63.0176 ± 2.5672^d

22.7509 ± 1.5763^c

A

13.5532 ± 4.4832^a

34.6422 ± 4.7805^c

71.3293 ± 3.7622^d

18.6287 ± 4.4183^b

E. rubra

Stem

H

10.1507 ± 1.5942^a

9.3007 ± 2.9967^a

8.2581 ± 3.1385^a

13.9341 ± 1.9361^a

D

23.3823 ± 1.3818^b

19.9153 ± 5.1146^b

14.7452 ± 1.9173^b

11.6367 ± 5.1136^a

A

12.7918 ± 0.9803^a

26.375 ± 0.3326^c

6.7183 ± 2.7161^a

14.7107 ± 2.2366^a

Leaves

H

56.1876 ± 2.6042^c

15.2167 ± 1.5197^d

9.5785 ± 2.3736^a

10.2952 ± 2.2208^a

D

16.7674 ± 2.6103^b

25.0321 ± 6.5080^c

14.0886 ± 1.1765^b

11.3583 ± 2.5385^a

E. revoluta

Stem

H

39.7867 ± 3.1283^c

24.4083 ± 2.0075^c

79.3285 ± 1.2329^d

14.1480 ± 1.3285^a

D

18.3568 ± 1.8974^b

13.7411 ± 2.1074^d

14.7673 ± 4.1305^b

10.6601 ± 1.9422^a

A

22.5015 ± 4.4417^b

6.9845 ± 1.2959^a

10.7772 ± 0.6380^a

11.0185 ± 3.4961^a

E. pulverulenta

Stem

H

17.7417 ± 1.5066^b

7.5154 ± 1.9235^a

11.2879 ± 3.2494^b

17.3630 ± 8.3298^b

D

95.1946 ± 10.9158^d

24.3763 ± 2.4381^c

20.3552 ± 8.8824^c

12.0393 ± 1.7299^a

A

24.0417 ± 2.5179^b

23.9766 ± 1.0591^b

23.0374 ± 4.3020^c

11.8085 ± 1.8638^a

Leaves

H

20.3313 ± 1.6390^b

19.458 ± 2.0729^b

21.4674 ± 3.9661^c

32.1562 ± 14.5701^d

D

55.4643 ± 7.1389^d

13.6433 ± 1.9642^d

22.6237 ± 4.5147^c

13.9832 ± 0.8228^a

A

15.0914 ± 1.7535^b

22.9409 ± 9.5515^b

22.8511 ± 7.6715^c

18.0282 ± 2.5183^b

Flowers

H

15.4196 ± 2.8012^a

30.2962 ± 3.7342^c

18.5459 ± 2.5133^c

15.2301 ± 3.4980^b

D

9.3985 ± 1.8046^a

9.3284 ± 3.7723^a

8.6317 ± 2.9129^a

13.8068 ± 2.7420^a

A

19.7591 ± 4.4834^b

13.4092 ± 3.8624^d

19.5506 ± 3.8179^c

11.3231 ± 3.1435^a

E

15.9509 ± 2.2752^a

14.7024 ± 0.9387^d

20.5502 ± 4.7137^c

15.2715 ± 3.3880^b