Fig. 3
Schematic summary of the main findings of this work. (a) ErSA selectivity for the prostate cancer (PC-3) cell line; and (b) EpSH extract selectivity for the colon cancer (HT-29) cell line. In both cases, when compared to the non-tumor cell line (HEK-293T). Symbols represent the obtained results compared to the control of each experiment; (=): no change compared with the control; Green arrow: increase compared with the control; Red arrow: decrease compared with the control; ROS: reactive oxygen species; TRAP: total reactive antioxidant power; MDA: lipoperoxidation (malondialdehyde); SOD: superoxide dismutase; CAT: catalase; GSH/GSSG: GSH/GSSG ratio; O2.-: superoxide radical; H2O2: hydrogen peroxide; H2O: wáter; ΔΨmt: mitochondrial membrane potential; Nrf2: nuclear factor erythroid 2–related factor 2; FOXO3a: transcription factor forkhead box O-3 a