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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

Fig. 3

Diosmin reduces TGF-β1 induced inflammation and fibrosis in HK-2 cells. A MTT assay detects the toxicity of Diosmin on HK-2 cells. B The mRNA expression levels of collagen I and (C) α-SMA. D Representative western blot analysis of collagen I and α-SMA. E Quantitative analysis of collagen I and (F) α-SMA. G The levels of IL-6, (H) IL-1β and (I) TNF-α in the supernatant. *p < 0.05, and ***p < 0.001 versus the control (DMSO) group; &p < 0.05, &&p < 0.01, and &&&p < 0.001 versus the TGF-β1 group; ns = no significance; Ctrl = control; Dios = 75uM

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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