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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

Fig. 2

Diosmin inhibits the UUO-induced collagen deposition and fibrosis. A Representative images of collagen I and α-SMA IHC staining. B Representative western blot analysis of collagen I and α-SMA. C Quantitative analysis of collagen I and D α-SMA. E The mRNA expression levels of collagen I and F α-SMA in the left kidney of mice. ***p < 0.0001 versus the Sham group; &&p < 0.01, and &&&p < 0.001 versus the UUO group; #p < 0.05, ##p < 0.01 and ###p < 0.001; ns = no significance; Scale bar = 100 μm. Dios-1 = Diosmin 50 mg/kg; Dios-2 = Diosmin 100 mg/kg

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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