Fig. 1

Diosmin attenuates UUO-induced renal injury and inflammation. A Representative images of HE staining and Masson staining of kidney tissue. B Scr and (C) BUN values for the different groups. D Quantification of Masson staining-positive areas. E Detection of protein expression levels of IL-6, (F) IL-1β and (G) TNF-α in the serum using Elisa. ^*p < 0.05, and ^***p < 0.001 versus the Sham group; ^&&p < 0.01, and ^&&&p < 0.001 versus the UUO group; ^#p < 0.05, ^##p < 0.01; ns = no significance; Scr = serum creatinine; BUN = blood urea nitrogen; Scale bar = 100 μm. Dios-1 = Diosmin 50 mg/kg; Dios-2 = Diosmin 100 mg