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Table 2 Association between number of GRADE factors adopted and strength and direction of recommendations of the included CPGs N (%)

From: Comprehensive consideration of multiple determinants from evidence to recommendations in guidelines for most traditional Chinese medicine was suboptimal: a systematic review

GRADE domain

GRADE recommendations

(n = 912)

TCM recommendations

(n = 2452)

Considereda

Considered and supported by evidencea

Considered as an independent dimensiona

Consideredb

Considered and supported by evidenceb

Considered as an independent dimensionb

Problem priority

426(46.7)

312(34.2)

426(46.7)

0(0.0)

0(0.0)

0(0.0)

Desirable anticipated effects

912(100.0)

842(92.3)

912(100.0)

2432(99.2)

2022(82.5)

2432(99.2)

Undesirable anticipated effects

912(100.0)

842(92.3)

912(100.0)

2432(99.2)

2022(82.5)

2432(99.2)

Balance between desirable and undesirable effects

912(100.0)

842(92.3)

912(100.0)

2432(99.2)

2022(82.5)

2432(99.2)

Certainty of the evidence

912(100.0)

842(92.3)

912(100.0)

2394(97.6)

2000(81.6)

2394(97.6)

Values and preferences

912(100.0)

353(38.7)

907(99.5)

403(16.4)

4(0.2)

403(16.4)

Resource requirements

515(56.5)

393(43.1)

465(51.0)

475(19.4)

6(0.2)

475(19.4)

Certainty of the evidence of resource requirements

359(39.4)

245(26.9)

358(39.3)

0(0.0)

0(0.0)

0(0.0)

Cost-effectiveness of the intervention

433(47.5)

202(22.1)

429(47.0)

2(0.1)

2(0.1)

2(0.1)

Health equity

466(51.1)

145(15.9)

431(47.3)

7(0.3)

2(0.1)

0(0.0)

Acceptability

493(54.1)

163(17.9)

431(47.3)

73(3.0)

0(0.0)

70(2.9)

Feasibility

496(54.4)

187(20.5)

436(47.8)

81(3.3)

4(0.2)

74(3.0)

Othersc

37(4.1)

36(3.9)

30(3.3)

28(1.1)

4(0.2)

21(0.9)

  1. GRADE Grading of Recommendations Assessment, Development and Evaluation, TCM Traditional Chinese Medicine
  2. aThe proportion of multiple items was compared to all 912 GRADE recommendations
  3. bThe proportion of multiple items was compared to all 2452 TCM recommendations
  4. chuman rights, policy, Regional compliance with the situation, the gap in the required clinical conditions and the practice, diagnostic accuracy, certainty of evidence for diagnostic accuracy, certainty of evidence for test effects, certainty of evidence of the management effect, certainty of evidence for diagnostic outcomes and management