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Table 1 Characteristic of included clinical practice guidelines N(%)

From: Comprehensive consideration of multiple determinants from evidence to recommendations in guidelines for most traditional Chinese medicine was suboptimal: a systematic review

The baseline characteristics of guidelines

GRADE CPGsa

(n = 45)

TCM CPGsb

(n = 262)

Totalc

(n = 307)

Type of guidelines

 Routine evidence-based guidelines

26(57.8)

234(89.3)

260(84.7)

 Rapid recommendations

16(35.6)

0(0.0)

16(5.2)

 Adaptation guideline

2(4.4)

6(2.3)

8(2.6)

 Living guideline

1(2.2)

0(0.0)

1(0.3)

 Non-evidence-based guideline

0(0.0)

22(8.4)

22(7.2)

Scope of guidelines

 Treatment

19(42.2)

118(45.0)

137(44.6)

 Diagnosis

1(2.2)

0(0.0)

1(0.3)

 Managementd

13(28.9)

7(2.7)

20(6.5)

 Treatment and diagnosis

1(2.2)

137(52.3)e

138(45.0)

 Prevention

6(13.3)

0(0.0)

6(2.0)

 Screening

3(6.7)

0(0.0)

3(1.0)

 Othersf

2(4.4)

0(0.0)

2(0.7)

Discipline

 Internal medicine

32(71.1)

157(59..9)

189(61.6)

 Surgery

3(6.7)

54(20.6)

57(18.6)

 Gynaecology or Andrology

1(2.2)

25(9.5)

26(8.5)

 Paediatrics

1(2.2)

18(6.9)

19(6.2)

 COVID-19

5(11.1)

3(1.1)

8(2.6)

 Othersg

3(6.7)

5(1.9)

8(2.6)

What to access using the GRADE approaches

 Certainty of evidence and strength and direction of the recommendation

45(100.0)

105(40.1)

150(48.9)

 Certainty of evidence

0(0.0)

14(5.3)

14(4.6)

 Strength and direction of the recommendation

0(0.0)

12(4.6)

12(3.9)

 Not applied

0(0.0)

131(50.0)

131(42.7)

Report certainty of evidence and strength and direction of the recommendations

 Report certainty of evidence and strength and direction of the recommendations

45(100.0)

202(77.1)

247(80.5)

 Only report the certainty of evidence

0(0.0)

5(1.9)

5(1.6)

 Only report the strength and direction of the recommendations

0(0.0)

20(7.6)

20(6.5)

 Neither reported

0(0.0)

35(13.4)

35(11.4)

  1. CPG clinical practice guidelines, GRADE Grading of Recommendations Assessment, Development and Evaluation, TCM Traditional Chinese Medicine
  2. aThe proportion of multiple items was compared to all 45 GRADE CPGs
  3. bThe proportion of multiple items was compared to all 262 TCM CPGs
  4. cThe proportion of multiple items was compared to all 307 CPGs
  5. dIt includes at least 2 kinds of recommendations in diagnosis, treatment, prevention, screening, detection, prognosis and life management
  6. eThe title of the guideline is defined as the treatment and diagnosis, but the diagnosis is the introduction of background information, and the recommendation is unrelated to the diagnosis
  7. fFor the application of the interventions: Transfusion strategies, lumbar puncture
  8. gTransfusion strategies, Ebola virus disease, lumbar puncture, stomatology, application of drugs