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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways

Fig. 6

Expression of tumor suppressor genes PPP3CC and GADD45 B in pan-cancer. A-B. Pan cancer gene expression profile of GADD45B and PPP3CC. Red boxplot depicts expression level in primary tumors, while blue boxplot indicate expression in normal samples. C-H. The expression distribution of GADD45B and PPP3CC in tumor and normal tissues from TCGA database. The downregulation of GADD45B and PPP3CC are not related to gender, race and tumor stages. The statistical differences of two and three groups were tested through the Wilcox test and Kruskal-Wallis test, respectively. **** represents p < 0.0001, *** represents p < 0.001, ** represents p < 0.01

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