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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways

Fig. 5

Shikonin increased tumor suppressor genes PPP3CC and GADD45B  in MAPK signaling. A-B. GADD45B and PPP3CC are activated after shikonin treatment in both A549 and H1299 cells by qPCR detection. C-D. The MAPK proteins, GADD45B and PPP3CC are activated after shikonin treatment in both A549 and H1299 cells by western blotting. The blots are cut prior to hybridisation with antibodies during blotting and the cropped plots are used in the figure to improve the clarity of presentation. *** represents p < 0.001, ** represents p < 0.01

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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