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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways

Fig. 3

Shikonin is related to TSG expression alterations through MAPK signaling. (A) A total of 1795 upregulated genes and by 1645 downregulated genes by Shikonin in A549 cells through mRNA sequencing analysis. (B) Heatmap of the top 100 changed genes by shikonin. (C) The upregulated genes are mainly involved in MAPK signaling pathway by KEGG profiling

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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