Fig. 1From: Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathwaysShikonin inhibits the cell viability of A549 and H1299 cells in dose-dependent manner. A. The chemical structure of shikonin. B-C. The cell viability of A549 and H1299 cells was determined by CCK8 assays. D. The respective IC50 in A549 and H1299 cells was calculated. E. The cell viability of HCoEpi cells was determined by a CCK8 assay. F-G. Shikonin was able to inhibit the cell growth of A549 and H1299 cells in a dose-dependent manner. **** represents p < 0.0001, *** represents p < 0.001Back to article page