Fig. 1

Effect of AS III on cell proliferation viability. (A) Cell viability and IC₅₀ curves of A549, H460 and BEAS-2B cells treated with different concentrations of AS III for 24 h (values represent mean + SD of triplicates. *P < 0.05, **P < 0.01, *** P < 0.001). (B) Cells were treated with the indicated concentrations of AS III (150 and 250 µmol/L) and DDP (40 µg/mL) for 24 h, followed by EdU staining. (C) A549 and H460 cells were treated with different concentrations of AS III (0, 50, 100, 200, 300, and 400 µmol/L) and DDP (0, 5, 10, 20, 30, and 40 µg/mL) for 24 h, and cell viability was determined by CCK-8