Comparison of chitosan nanoparticles containing Lippia citriodora essential oil and citral on the induction of apoptosis in A375 melanoma cells

Table 3 Ingredients of the prepared nanoparticles and their size analyses

Sample	Chitosan (%)	TPP¹ (%)	L. citriodora EO	Citral	tween 20 (%)	Particle size (nm)	SPAN²
1	0.2	0.1	0.16	_	0.24	403	0.98
2	0.2	0.1	_	0.16	0.24	267	0.96
3	0.2	0.1	_	_	0.24	245	0.99
4	0.2	0.8	0.16	_	0.24	391	3.5
5	0.2	0.8	_	0.16	0.24	275	0.97
6	0.2	0.8	_	_	0.24	238	1.2
7	0.2	0.6	0.16	_	0.24	667	1.4
8	0.2	0.6	_	0.16	0.24	708	1.4
9	0.2	0.6	_	_	0.24	532	0.99
10	0.2	0.4	0.16	_	0.24	258	1.7
11	0.2	0.4	_	0.16	0.24	202	0.99
12	0.2	0.4	_	_	0.24	146	0.98
13	0.2	0.2	0.16	_	0.24	94	0.98
14	0.2	0.2	_	0.16	0.24	35	0.94
15	0.2	0.2	_	_	0.24	30	0.97

¹Tripolyphosphate. ²Particle size distribution (value < 1 has a narrow distribution)

ISSN: 2662-7671