Fig. 6
From: Prevention of STAT3-related pathway in SK-N-SH cells by natural product astaxanthin
Influence of astaxanthin and the combination of astaxanthin and si-STAT3 on the growth of xenograft tumors. (a) Animal experiment results. Each group had six mice as parallel repeats. Numbers 1–6 represent the six mice used in the experiment to check the reproducibility of the results. (b) Animal experiment results. Astaxanthin and si-STAT3 both suppressed tumor growth. However, the repression effects were strengthened when astaxanthin and si-STAT3 were combined. The data from three experiments were used to calculate mean values (± SD). *P < 0.05, **P < 0.01, ***P < 0.001. (c) Results for tumor inhibition rate. (d) Cell apoptosis in tissues assessed using a TUNEL assay