Fig. 1

Antiproliferative effect of astaxanthin on SK-N-SH cells was studied using an MTT assay. (a) SK-N-SH cells were treated with 0, 50, 100, 200 and 400 µM astaxanthin for 48 h before the MTT assay was conducted. The data from three experiments were used to calculate mean values (± SD). *P < 0.05, **P < 0.01, ***P < 0.001. (b) Linear regression relationship between drug concentration and inhibition rate. IC50 was calculated as 387 using graphpad prism9