Table 4 Correlation of cancer cell sensitivity to Alg-EO, Alg-Beta, F. gummosa EO, and β-pinene with Bax/Bcl-2 ratio in normoxic and hyperoxic conditions

Sample

Bax

Bcl-2

Bax/Bcl-2 ratio

Susceptibility*

Bax

Bcl-2

Bax/Bcl-2 ratio

Susceptibility*

Alg-EO

1.99

0.60

3.31

+++

4.31

0.35

12.44

++++

Alg-Beta

1.82

0.65

2.81

++

2.56

0.46

5.53

+++

EO

1.32

0.83

1.58

+

1.43

0.81

1.75

+

β-pinene

1.56

0.78

2.00

+

1.58

0.71

2.23

++

MDA-MB-231 cells

Normoxic

Hyperoxic

SAMPLES

Bax

Bcl-2

Bax/Bcl-2 ratio

Susceptibility*

Bax

Bcl-2

Bax/Bcl-2 ratio

Susceptibility*

Alg-EO

1.83

0.61

2.99

++

1.73

0.54

3.20

+++

Alg-Beta

1.76

0.56

3.17

+++

1.80

0.61

2.95

++

EO

1.43

0.72

2.00

+

1.49

0.67

2.24

++

β-pinene

1.33

0.77

1.72

+

1.27

0.80

1.59

+