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Table 4 The cytotoxic activities of methanol extract, fractions, and isolated compounds on cancerous and normal cell lines by MTT assay

From: Isolation and structure elucidation of the compounds from Teucrium hyrcanicum L. and the investigation of cytotoxicity, antioxidant activity, and protective effect on hydrogen peroxide-induced oxidative stress

samples

Cell line

 

MCF7b

A431

HepG2

Hu02

MEa

392.5 ± 20c

 > 500

 > 500

 > 500

HF

459.5 ± 17.1

 > 500

 > 500

 > 500

EF

326.6 ± 36.6

235.4 ± 34.8

 > 500

 > 500

MF

 > 500

 > 500

 > 500

 > 500

Acteoside

32 ± 0.54

103 ± 1.65

194.6 ± 1.22

 > 500

Quercetin

389.60 ± 16.6

132.32 ± 12.1

338.3 ± 36.3

 > 500

  1. aME methanol extract, HF hexane fraction, EF ethyl acetate fraction, MF methanol fraction
  2. bMCF 7 (breast ductal carcinoma), A431 (epidermoid carcinoma), HepG2 (hepatocellular carcinoma)
  3. cIC50: required concentration of each sample to inhibit cell proliferation by 50% expressed as μg.ml−1; IC50 ± standard deviation (data from three experiments)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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