Fig. 2

Key target genes of atorvastatin against atherosclerosis and NSCLC. A Volcano map of the expression of 15 identical pathogenic genes between normal tissues and atherosclerosis groups in the GEO database: the red represents the up-regulated genes in atherosclerosis tissues, and the green represents the down-regulated genes. B Volcano map of the expression of 15 same pathogenic genes in NSCLC; The red represents the upregulated genes in the NSCLC tissues and the green represents the down regulated genes. C Find 4 genes (MMP9, MMP12, CD36, and FABP4) were as potential therapeutic targets of atorvastatin for atherosclerosis and NSCLC through overlapped the genes of atorvastatin related targets, DEGs of atherosclerosis and DEGs of NSCLC. D Expression of four common genes associated with atorvastatin against atherosclerosis and NSCLC in various cancers