Tissues | Parameters | Control | DM | DM + SP-100 | DM + SP-200 | DM + SP-400 | DM + Gly-3 |
---|---|---|---|---|---|---|---|
Liver | MDA (nmol/g prt) | 0.61 ± 0.02 | 0.76 ± 0.02** | 0.70 ± 0.04 | 0.60 ± 0.02## | 0.63 ± 0.02# | 0.62 ± 0.01## |
GSH (GSH/mg prt) | 92.56 ± 1.46 | 76.79 ± 3.06**** | 84.93 ± 1.82 | 80.65 ± 1.36 | 85.23 ± 2.10# | 85.07 ± 1.22# | |
GST (nmol/g prt) | 155.83 ± 2.17 | 144.14 ± 2.43 | 148 ± 6.44 | 138.79 ± 3.56 | 162.24 ± 5.32 | 149.61 ± 3.72 | |
GR (U/g prt) | 2.90 ± 0.06 | 2.61 ± 0.11 | 2.83 ± 0.07 | 2.83 ± 0.12 | 3.13 ± 0.10## | 2.87 ± 0.05 | |
CAT (nmol/g prt) | 24.71 ± 1.13 | 20.93 ± 0.61* | 22.42 ± 0.93 | 19.39 ± 0.98 | 20.65 ± 0.60 | 21.01 ± 0.60 | |
SOD (pg/mg prt) | 266.19 ± 19.95 | 223.40 ± 18.40 | 233.83 ± 11.82 | 295.97 ± 57.52 | 246.97 ± 19.03 | 226.47 ± 9.25 | |
GPx (IU/mg prt) | 34.24 ± 4.04 | 29.3 ± 0.46 | 36.02 ± 2.77 | 32.4 ± 3.90 | 38.13 ± 2.02 | 44.08 ± 3.74# | |
Kidney | MDA (nmol/g prt) | 1.21 ± 0.06 | 1.63 ± 0.04**** | 1.32 ± 0.07### | 1.39 ± 0.03# | 1.27 ± 0.04### | 1.27 ± 0.04#### |
GSH (GSH/mg prt) | 119.81 ± 6.45 | 108.04 ± 3.53 | 115.47 ± 3.04 | 119.46 ± 1.32 | 119.48 ± 3.01 | 119.52 ± 3.67 | |
GST (nmol/g prt) | 19.01 ± 0.33 | 17.55 ± 0.88 | 18.16 ± 1.17 | 20.40 ± 1.12 | 20.15 ± 0.29 | 17.20 ± 0.93 | |
GR (U/g prt) | 6.38 ± 0. 18 | 5.73 ± 0.17 | 6.23 ± 0.26 | 6.11 ± 0.21 | 5.77 ± 0.19 | 6.07 ± 0.23 | |
CAT (nmol/g prt) | 12.86 ± 0.52 | 10.73 ± 0.51 | 10.79 ± 0.49 | 11.80 ± 0.39 | 11.25 ± 0.51 | 11.67 ± 0.51 | |
SOD (pg/mg prt) | 678.68 ± 60.81 | 429.74 ± 24.48** | 455.23 ± 33.41 | 523.70 ± 33.56 | 473.36 ± 26.67 | 459.07 ± 45.30 | |
GPx (IU/mg prt) | 105.83 ± 15.09 | 61.66 ± 4.04** | 63.02 ± 4.28 | 75.08 ± 5.84 | 68.20 ± 4.31 | 82.25 ± 7.20 | |
Pancreas | MDA (nmol/g prt) | 3.09 ± 0.14 | 4.45 ± 0.19** | 4.30 ± 0.15 | 4.10 ± 0.31 | 3.21 ± 0.40# | 3.40 ± 0.24 |
GSH (GSH/mg prt) | 173.13 ± 11.26 | 89.98 ± 9.22**** | 105.50 ± 7.23 | 129.66 ± 12.46 | 149.49 ± 13.76## | 131.23 ± 8.15 | |
GST (nmol/g prt) | 25.69 ± 2.13 | 15.61 ± 1.22* | 13.43 ± 0.93 | 23.32 ± 2.92 | 28.32 ± 2.55## | 21.25 ± 1.31 | |
GR (U/g prt) | 7.08 ± 0.42 | 5.33 ± 0.46 | 7.08 ± 0.50 | 5.18 ± 0.46 | 6.54 ± 0.29 | 5.94 ± 0.38 | |
CAT (nmol/g prt) | 4.27 ± 0.14 | 1.71 ± 0.12**** | 2.22 ± 0.13 | 3.82 ± 0.18#### | 3.84 ± 0.31#### | 3.66 ± 0.25#### | |
SOD (pg/mg prt) | 1509.41 ± 118.91 | 1485.23 ± 162.85 | 2184.34 ± 276.28 | 2501.17 ± 270.30# | 1712.02 ± 187.39 | 2575.47 ± 263.70# | |
GPx (IU/mg prt) | 185.71 ± 16.40 | 180.51 ± 8.49 | 239.86 ± 34.13 | 282.10 ± 26.28 | 230.63 ± 27.36 | 324.05 ± 37.99# |