Fig. 5

Microscopic image of pancreatic tissue. Control group had normal histological architecture (A). Severe necrotic cells were found in the DM (B), DM + SP-100 (C), and DM + SP-200 (D), moderate necrotic cells were found in the DM + SP-400 (E) and DM + Gly (F) groups. H&E 400x. Data are presented as mean ± standard error of mean (SEM). Control vs. DM: ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 and ^****P < 0.0001; DM vs. all treatment groups: ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 and ^####P < 0.0001