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Table 1 The effect of gallic acid on the plasma liver function parameters following uranyl acetate-induced liver dysfunction in rats

From: Gallic acid rescues uranyl acetate induced-hepatic dysfunction in rats by its antioxidant and cytoprotective potentials

Parameters/Groups

Control

UA

GA + UA

P value

Plasma ALT activity (U/L)

9.007 ± 0.389

8.604 ± 0.222

9.063 ± 0.206

0.474

Plasma AST activity (U/L)

0.141 ± 0.011

0.222 ± 0.020#

0.146 ± 0.017&

0.0150

Plasma LDH activity (U/L)

24.645 ± 3.170

227.880 ± 76.316#

65.410 ± 9.306&

0.011

Plasma albumin level (g/dl)

2.836 ± 0.106

2.939 ± 0.061

2.954 ± 0.188

0.785

Plasma globulin level (g/dl)

1.790 ± 0.159

3.850 ± 0.524#

4.422 ± 0.813Ω

0.004

Plasma TP level (g/dl)

4.693 ± 0.205

6.375 ± 0.613#

7.536 ± 0.800Ω

0.009

Plasma glucose level (mg/dl)

87.594 ± 15.807

193.892 ± 20.750#

116.462 ± 22.152&

0.003

  1. UA: uranyl acetate; GA: gallic acid; AST: aspartate aminotransferase; ALT: Alanine aminotransferase; LDH: lactate dehydrogenase; TP: Total protein
  2. Results are expressed as mean ± SEM of 6 rats per group (One-way ANOVA followed by Duncan post-test)
  3. #= significant difference between UA and the control groups
  4. &= significant difference between GA + UA and UA groups
  5. Ω = significant difference between GA + UA and the control groups
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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