Fig. 4

Collagen fibers examination in the experimental groups. (a-c) photomicrographs of liver sections stained by Picrosirius red stain, bar = 50 μm. (a) In control group, showing tiny amount of collagen fibers around the central vein. (b) In UA group, showing huge amount of collagen fibers represented by the red color. (c) In GA + UA group, showing few amounts of collagen fibers nearly as those of control group. (d) Percentage of area of collagen fibers in the different experimental groups. Results are expressed as mean ± SEM of 3 rats per group (One-way ANOVA followed by Duncan post-test). # significant difference between UA and the control groups. & significant difference between GA + UA and UA groups