Brazilian green propolis prevent Alzheimer’s disease-like cognitive impairment induced by amyloid beta in mice

Table 2 Genes suppressed by Brazilian green propolis treatment in the prefrontal cortex

Gene Symbol	Gene Accession	Value (Log₂ Ratio)			Log Ratio ¹⁾	p-value ¹⁾	Log Ratio ²⁾	p-value ²⁾
Gene Symbol	Gene Accession	Sham	Aβ	Aβ + PP900	Log Ratio ¹⁾	p-value ¹⁾	Log Ratio ²⁾	p-value ²⁾
Trem2	NM_001272078	6.8	7.8	6.9	0.97	0.011	‒0.85	0.019
Gbp3	NM_001289492	5.2	6.0	5.6	0.87	0.00	‒0.44	0.036

¹⁾ Log ratio between the sham and Aβ groups, p-value determined using Student’s t-test
²⁾ Log ratio between the Aβ and Aβ + PP900 groups, p-value determined using Student’s t-test
Sham group [sham operation plus vehicle (0.5% methylcellulose) treatment]; Aβ group (ICV Aβ_25‒35 injection plus vehicle treatment); Aβ + PP900 group (ICV Aβ_25‒35 injection plus 900 mg/kg b.w. Brazilian green propolis)

ISSN: 2662-7671