Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest

Table 6 Hepatotoxicity prediction of diosbulbin C and reference drugs

Compound	Hepatotoxic	Prediction	Applicability #MD	Applicability #Mdpvalue
Diosbulbin C	-5.52164	FALSE	10.3491	0.0398
Cisplatin	0.891281	TRUE	9.01983	0.4470
Carboplatin	-4.24153	FALSE	7.78939	0.9326
Gefitinib	-3.99306	TRUE	14.2139	2.99E-09
Paclitaxel	-9.53069	FALSE	16.426	3.21E-15
Adriamycin	1.42634	TRUE	14.8384	7.86E-11

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