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Table 4 Aqueous solubility prediction of diosbulbin C and reference drugs

From: Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest

Compound

Solubility

Solubility Level

Diosbulbin C

-2.779

3 (yes, good)

Cisplatin

0.776

5 (no, too soluble)

Carboplatin

-0.553

4 (yes, optimal)

Gefitinib

-5.561

2 (yes, low)

Paclitaxel

-3.515

3 (yes, good)

Adriamycin

-4.798

2 (yes, low)