Table 3 Blood brain barrier penetration and human intestinal absorption prediction of diosbulbin C and reference drugs

Diosbulbin C

-1.644

3 (low)

0 (good absorption)

0.640

106.647

Cisplatin

-

4 (undefined)

2 (low absorption)

-0.311

0

Carboplatin

-1.184

3 (low)

0 (good absorption)

0.569

76.232

Gefitinib

0.109

1 (high)

0 (good absorption)

4.203

65.474

Paclitaxel

-

4 (undefined)

3 (very low absorption)

3.055

223.712

Adriamycin

-

4 (undefined)

3 (very low absorption)

-0.044

209.310