Table 3 In silico ADMET properties of phytochemicals of Myrtus communis L. by admetSAR

(A)Esculin

0.6058

0.5202

Non-substrate/ Non-inhibitor

Mitochondria

Weak

alpha-Bulnesene

0.9723

0.9940

Non-substrate/ Non-inhibitor

Lysosome

Weak

alpha-Cadinol

0.9455

1.0000

Non-substrate/ Non-inhibitor

Lysosome

Weak

Estragole

0.9383

0.9939

Non-substrate/ inhibitor

Mitochondria

Weak

Benzyl valerate

0.9739

1.0000

Non-substrate/ Non-inhibitor

Plasma membrane

beta-Bourbonene

0.9612

0.9934

Non-substrate/ Non-inhibitor

Lysosome

Weak

beta-Chamigrene

0.9554

0.9875

Non-substrate/ Non-inhibitor

Lysosome

Weak

(Z)-gamma-Bisabolene

0.9399

0.9934

Non-substrate/ Non-inhibitor

Lysosome

Weak

Carvacrol

0.9381

0.9955

Non-substrate/ Non-inhibitor

Mitochondria

Weak

Ellagic acid

0.5641

0.7199

Non-substrate/ Non-inhibitor

Mitochondria

Weak

Humulene epoxide II

0.9674

1.0000

Non-substrate/ inhibitor

Lysosome

Weak

Isobornyl acetate

0.9719

0.9969

Non-substrate/ Non-inhibitor

Mitochondria

Weak

Juniper camphor

0.9455

1.0000

Non-substrate/ Non-inhibitor

Lysosome

Weak

Linalyl anthranilate

0.9014

0.9669

Non-substrate/ Non-inhibitor

Lysosome

Weak

Myrtenyl acetate

0.9002

0.9950

Non-substrate/ Non-inhibitor

Lysosome

Weak

Myrtucommulone A

0.6582

0.9790

Non-substrate/ inhibitor

Mitochondria

Weak

Myrtucommulone B

0.5297

0.9687

Non-substrate/ inhibitor

Mitochondria

Weak

Patuletin

0.8171

0.9482

Non-substrate/ Non-inhibitor

Mitochondria

Weak

p-Cymen-8-ol

0.9741

0.9944

Non-substrate/ Non-inhibitor

Mitochondria

Weak

p-Cymol

0.9677

0.9960

Non-substrate/ Non-inhibitor

Lysosome

Weak

Semimyrtucommulone

0.6582

0.9790

Non-substrate/ inhibitor

Mitochondria

Weak

Spathulenol

0.9648

0.9913

Non-substrate/ inhibitor

Lysosome

Weak

Terpinolene

0.9299

0.9963

Non-substrate/Non-inhibitor

Lysosome

Weak