Table 2 The serum components of Shaoyao decoction identified by UHPLC LC–MS/MS

1

Caffeoyl quinic acid

phenylpropanoids

0.74079167

C16H18O9

2

( +)-Erythraline

alkaloid

0.78200333

C18H19NO3

3

Quercetin-3-O-glucoside

flavonoids

0.823825

C21H20O12

4

Uracil

Diazines

0.91588333

C4H4N2O2

5

Luteolin-4'-O-glucoside

flavonoids

1.07522

C21H20O11

6

Feruloyl quinic acid

phenylpropanoids

1.14350333

C17H20O9

7

Mearnsitrin

flavonoids

1.20659917

C22H22O12

8

Ellagic acid

phenylpropanoids

1.33214

C14H6O8

9

o-Xylene

Benzene and substituted derivatives

1.36274

C8H10

10

7-methoxy-9,10-dihydrophenanthrene-2,5-diol

Phenanthrenes and derivatives

1.53223333

C15H14O3

11

Scutellarein

flavonoids

1.59420917

C15H10O6

12

Liquiritin

flavonoids

1.69193333

C21H22O9

13

4',5,7-Trihydroxy-6,8-diprenylisoflavone

flavonoids

2.14363333

C25H26O5

14

MORIN

flavonoids

2.333425

C15H10O7

15

Herbacetin

flavonoids

2.64415

C15H10O7

16

Fisetin

flavonoids

2.77781667

C15H10O6

17

Dihydroluteolin

flavonoids

2.78606667

C15H12O6

18

5,7-Dihydroxy-4-methylcoumarin

phenylpropanoids

2.93575

C10H8O4

19

Emodin

quinones

3.16304167

C15H10O5

20

2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol

phenylpropanoids

3.25765833

C20H26O6

21

Cepharadione B

isoquinoline alkaloid

3.29373333

C19H15NO4

22

N-Acetylanonaine

alkaloid

3.34033333

C19H17NO3

23

Kaempferol 3-O-sulfate

flavonoids

3.4755

C15H10O9S

24

Apigenin

flavonoids

3.54954167

C15H10O5

25

Estragole

Phenol ethers

3.68065833

C10H12O

26

Coumestrol

phenylpropanoids

3.88778333

C15H8O5

27

Sanggenon H

flavonoids

3.91865

C20H18O6

28

Wedelolactone

phenylpropanoids

3.92528333

C16H10O7

29

Hexamethylquercetagetin

flavonoids

4.53515

C21H22O8

30

Flavone base + 3O, O-HexA

flavonoids

4.77920833

C21H18O11

31

Isoliquiritigenin

flavonoids

4.863

C15H12O4

32

1,2-Dihydroxy anthraquinone

quinones

4.86436667

C14H8O4

33

Silybin

flavonoids

5.24036667

C25H22O10

34

Jaceosidin

flavonoids

5.47153333

C17H14O7

35

Licoflavanone

flavonoids

5.47176667

C20H20O5

36

Berlambine

alkaloid

5.62416667

C20H17NO5

37

calycosin

flavonoids

5.82869167

C16H12O5

38

6-Oxochelerythrine

alkaloid

6.04055

C21H17NO5

39

Pinocembrin

flavonoids

6.20543333

C15H12O4

40

(1alpha,6alpha,7alphaH)-2,4(15)-Copadiene

terpenoids

6.452675

C15H22

41

Flavone base + 40, 1Prenyl

flavonoids

6.46931667

C20H18O6

42

Licoricesaponin K2

terpenoids

6.603075

C42H62O16

43

Phloretin

flavonoids

6.68948333

C15H14O5

44

Carpachromene

flavonoids

7.476025

C20H16O5

45

Isoglycyrol

phenylpropanoids

7.50083333

C21H18O6

46

Tri-N-butyl phosphate; CE30; STCOOQWBFONSKY-UHFFFAOYSA-N

Organic phosphoric acids and derivatives

9.11573333

C12H27O4P

47

Alnustone

Diarylheptanoids

12.3221667

C19H18O

48

Withanolide A

terpenoids

12.6997

C28H38O6

49

Terfenadine

alkaloid

13.832

C32H41NO2