Fig. 5

Hub network and DisGeNET enrichment analysis. A Compound-Target-Pathway network of L. sinense. The orange rectangles represent the small molecular components in L. sinense. The blue circles represent the relevant targets. The red V nodes represent the relevant signalling pathways. The edges represent the relationship among compounds, targets and pathways. The node size is proportional to the node degree in the network, and the width and colour of the edges is proportional to the edge betweenness centrality. B Hub network identified from the CTP network using the CytoHubba. Colour node indicates the degree value of each node in the network. C DisGeNET enrichment analysis of hub targets. The size of the dots refers to the number of genes enriched for that disease (the greater the number of genes, the larger the dot). The FDR is defined by a colour scale, the closer it is to red, the greater the FDR value and the greater the association