Skip to main content

Table 3 Within- and between-group comparisons in the frequency of gastrointestinal symptoms during the 12-week intervention

From: The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: a double-blind randomized placebo-controlled trial

 

Ginger (n = 26)

Placebo (n = 26)

P-value b

Baseline

Endpoint

Change

P-value a

Baseline

Endpoint

Change

P-value a

Anorexia

19.23 ± 4.45

19.48 ± 3.96

0.25 ± 3.40

0.51

13.46 ± 4.21

15.87 ± 4.56

2.41 ± 3.08

0.52

0.70

Dysphagia

4.81 ± 1.97

3.92 ± 1.80

-0.89 ± 2.94

0.77

11.54 ± 4.44

10.73 ± 3.95

-0.81 ± 1.69

0.64

0.44

Heartburn

22.11 ± 5.25

16.48 ± 5.69

-5.63 ± 4.46

0.22

11.54 ± 3.17

16.62 ± 4.55

5.08 ± 3.10

0.11

0.12

Nausea

13.46 ± 3.98

1.05 ± 0.96

-12.41 ± 3.75

0.003

5.77 ± 2.52

9.52 ± 3.08

3.75 ± 1.82

0.043

< 0.001

Abdominal pain

13.46 ± 3.98

11.70 ± 3.44

-1.76 ± 3.65

0.75

10.58 ± 4.20

14.75 ± 4.80

4.17 ± 2.26

0.078

0.25

Bloating

33.65 ± 5.54

24.34 ± 5.04

-9.31 ± 4.44

0.046

28.85 ± 5.31

30.41 ± 5.26

1.56 ± 4.05

0.70

0.098

Belching

21.15 ± 4.53

20.52 ± 4.11

-0.63 ± 3.81

0.87

13.46 ± 4.43

21.82 ± 5.41

8.36 ± 3.30

0.018

0.15

Flatulence

31.73 ± 4.71

31.38 ± 4.54

-0.35 ± 5.83

0.95

28.85 ± 4.74

28.15 ± 4.37

-0.70 ± 2.91

0.81

0.74

Constipation

39.42 ± 6.53

15.79 ± 4.98

-23.63 ± 5.36

< 0.001

18.27 ± 4.91

33.08 ± 5.77

14.81 ± 2.78

< 0.001

< 0.001

Diarrhea

6.73 ± 2.61

6.95 ± 2.20

0.22 ± 2.41

0.93

10.58 ± 3.71

11.16 ± 4.16

0.58 ± 4.74

0.90

0.53

  1. Note: Data are expressed as mean ± standard error
  2. Note: Data were measured using the visual analogue scale ranging from 0 to 100 mm
  3. a Obtained from the paired t-test
  4. b Obtained from the analysis of covariance adjusted for baseline values