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Table 2 Participants’ baseline characteristics

From: A crossover randomized controlled trial examining the effects of black seed (Nigella sativa) supplementation on IL-1β, IL-6 and leptin, and insulin parameters in overweight and obese women

Variable

Overall (n = 46)

Group A a (n = 23)

Group B b (n = 23)

Baseline P value c

Age (years) d

36.50 (9.40)

37.70 (10.91)

34.60 (9.60)

0.35

Height (cm) d

158.74 (6.61)

156.50 (4.51)

159.60 (7.20)

0.08

Body Weight (kg) d

76.80 (13.90)

76.60 (13.90)

79.93 (14.8)

0.47

BMI (kg/m2) d

31.26 (4.80)

31.15 (4.13)

31.40 (5.50)

0.91

Physical activity (MET- h/day) d

25.72 (3.25)

25.91 (3.10)

25.54 (3.90)

0.67

Menopause status, (perimenopause) n (%)

8 (17.17)

3 (13.10)

5 (20.90)

0.48

Mild fatty liver, n (%)

17 (36.17)

8 (34.78)

9 (37.50)

0.51

High normal blood pressure, n (%)

7 (14.90)

2 (8.70)

5 (20.85)

0.25

Family history of obesity, n (%)

10 (25.64)

5 (26.31)

5 (25.10)

0.31

Dietary intakesd

Energy intake (kcal)

1780.34 (190.54)

1765.86 (212.82)

1794.25 (169.56)

0.61

Carbohydrate (gr)

222.14 (34.153)

217.25 (31.89)

226.82 (37.10)

0.35

Protein (gr)

50.90 (7.80)

52.68 (8.21)

49.21 (7.30)

0.13

Fat (gr)

79.30 (12.57)

79.70 (12.30)

78.9 (13.10)

0.84

Fiber (gr)

13.11 (2.80)

12.50 (2.95)

13.85 (2.51)

0.11

Cholesterol (mg)

144.98 (862.70)

162.43 (93.54)

128.26 (78.80)

0.18

PUFA (gr)

25.43 (5.10)

25.76 (4.74)

25.11 (5.40)

0.67

MUFA (gr)

32.20 (6.50)

31.33 (6.21)

33.10 (6.75)

0.37

SFA (gr)

14.90 (2.80)

15.26 (2.25)

14.64 (3.31)

0.51

Vitamin E (α-tocopherol) (IU)

26.01 (5.60)

25.93 (5.30)

26.11 (5.96)

0.91

Vitamin C (mg)

59.95 (24.38)

56.71 (20.61)

63.14 (27.59)

0.38

Vitamin D (μg)

3.80 (2.70)

4.10 (2.80)

3.50 (2.50)

0.48

Medication use

Statins, n (%)

10 (21.27)

5 (21.73)

5 (20.84)

0.31

Blood pressure lowering drugs, n (%)

3 (6.38)

0 (0.0)

3 (12.50)

Both drugs, n (%)

6 (12.78)

3 (13.10)

3 (15.50)

No drugs, n (%)

20 (421.55)

11 (47.82)

9 (37.50)

Serum Biomarkersd

IL-1β (pg/ml)

2.95 (1.42)

2.75 (1.45)

3.00 (1.40)

0.42

IL-6 (pg/ml)

2.85 (1.52)

2.70 (1.50)

1.85 (0.50)

0.76

Leptin (ng/ml)

41.30 (6.80)

41.90 (6.22)

40.80 (7.31)

0.63

Insulin (μU/m)

6.42 (0.79)

6.18 (0.93)

6.29 (0.87)

0.56

  1. a Participants who started with NS supplementation and then went on to placebo
  2. b Participants who started with placebo and then went on to NS supplementation
  3. c Independent t test was used to compare between-group measurements
  4. d Data are shown in Mean ± SD