Anti-microbial and anti-cancer efficacy of acetone extract of Rosa chinensis against resistant strain and lung cancer cell line

Table 2 Anti-microbial activity of RE against different ESBL resistant K.pneumonia isolates using disc diffusion method. % of biofilm inhibition at 1000 µg/ml and IC₅₀ value of biofilm inhibition of RE against various resistant strains of K.pneumonia isolates. Results were expressed in Mean ± SD

S.NO	Resistant Cultures	Zone of inhibition (mm)				% of inhibition of biofilm formation at 1000 µg/ml	IC₅₀ Value in inhibiting the biofilm formation
S.NO	Resistant Cultures	25 µg/ml	50 µg/ml	75 µg/ml	100 µg/ml	% of inhibition of biofilm formation at 1000 µg/ml	IC₅₀ Value in inhibiting the biofilm formation
1	R1	6.7 ± 0.63	7.1 ± 0.81	7.5 ± 0.09	8.2 ± 0.081	62.06 ± 0.45	26.5 ± 0.45 µg/ml
2	R2	3.5 ± 0.009	4.2 ± 0.9	5.3 ± 0.072	6.5 ± 0.009	48.38 ± 0.63	51.8 ± 0.63 µg/ml
3	R3	4.3 ± 0.045	5.4 ± 0.45	6.1 ± 0.45	6.8 ± 0.18	60.71 ± 0.63	37.89 ± 0.63 µg/ml
4	R4	4.5 ± 0.072	5.6 ± 0.081	6.2 ± 0.072	6.9 ± 0.018	40 ± 1.8	66.09 ± 1.8 µg/ml

ISSN: 2662-7671