Fig. 7

Effects of α-solanine on the proliferation of U87MG cells. a-d Morphological changes of U87MG cells treated with 0, 5, 10, and 15 µM of α-solanine for 24 h, respectively. e α-solanine inhibited the viability of U87MG cells as measured by the CCK8 assay. Data are presented as mean ± SD for three independent experiments. f Dose–response curve in the CCK8 assay of U87MG cells treated with α-solanine, yielding a calculated IC50 of 11.69 µM. *P < 0.05, ** P < 0.01, ns:not significant