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Table 2 Comparison of the time to onset of acquired resistance

From: A real-world study and network pharmacology analysis of EGFR-TKIs combined with ZLJT to delay drug resistance in advanced lung adenocarcinoma

 

Combined group

Monotherapy group

Z

P

Total time of resistance onset (days)

426.00 (372.25, 773.75)

328.00 (158.00, 568.50)

-3.06

0.01

First generation drug resistance (days)

439.50 (374.25, 743.75)

353.50 (218.00, 598.00)

-2.06

0.04

Second generation drug resistance (days)

597.50 (363.25, 892.50)

111.50 (111.00, 112.00)

-1.85

0.06

Third generation drug resistance (days)

392.50 (212.50, 810.50)

289.00 (166.50, 466.00)

-1.27

0.21

  1. Data are mean median (IQR)