Table 1 Baseline characteristics comparison of the two groups

n

40

49

Age (years)

59.25 ± 12.24

56.53 ± 8.57

1.19

0.24

Sex

2.71

0.1

 Males

31 (77.5%)

30 (61.2%)

 Females

9 (22.5%)

19 (38.8%)

Surgery or not

0.1

0.75

 Yes

11 (27.5%)

15 (30.6%)

 No

29 (72.5%)

34 (69.4%)

Staging

1.14

0.57

 IIIc

8 (20.0%)

6 (12.2%)

 Iva

25 (62.5%)

32 (65.3%)

 Ivb

7 (17.5%)

11 (22.4%)

Tumor location

2.37

0.67

 Right upper lobe

12 (30.0%)

18 (36.7%)

 Right middle lobe

7 (17.5%)

7 (14.3%)

 Right lower lobe

8 (20.0%)

5 (10.2%)

 Left upper lobe

8 (20.0%)

10 (20.4%)

 Left lower lobe

5 (12.5%)

9 (18.4%)

EGFR-TKI type

1.52

0.52

 First generation

28 (70.0%)

34 (69.4%)

 Second generation

4 (10.0%)

2 (4.1%)

 Third generation

8 (20.0%)

13 (26.5%)

  AST(U/L)

25.5 (20.0, 39.0)

27.0 (18.5, 37.0)

-0.82

0.41

  ALT(U/L)

22.5 (17.3, 49.0)

28.0 (17.0, 43.0)

-0.042

0.68

  CREA(μmoI/L)

58.0 (54.8, 71.0)

59.5 (48.7, 67.0)

-0.66

0.51

  TBIL(μmoI/L)

11.3 (9.7, 13.2)

13.0 (9.4, 16.1)

-1.09

0.27

  ALB(g/L)

40.5 (37.0, 44.5)

40.4 (37.2, 44.1)

-0.11

0.92

  BUN(mmol/L)

4.6 (3.9, 5.6)

4.8 (3.9, 5.7)

-0.37

0.71