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Table 2 Different combination ratios between MTX IC50 and (D4& D7) formulas each alone

From: Caffeine-folic acid-loaded-chitosan nanoparticles combined with methotrexate as a novel HepG2 immunotherapy targeting adenosine A2A receptor downstream cascade

IC50

0.5 MTX

1 MTX

2 MTX

0.5 D4

0.5 + 0.5

0.5 + 1

0.5 + 2

1 D4

1 + 0.5

1 + 1

1 + 2

2 D4

2 + 0.5

2 + 1

2 + 2

0.5 D7

0.5 + 0.5

0.5 + 1

0.5 + 2

1 D7

1 + 0.5

1 + 1

1 + 2

2 D7

2 + 0.5

2 + 1

2 + 2

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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