Fig. 7

A Principal components analysis (PCA) score plots of metabolites in serum of naïve mice (veh), vancomycin pre-treated (van), metronidazole pre-treated (met), ampicillin pre-treated (amp), neomycin pre-treated (neo) and the cocktail (VMAN) pre-treated mice. The points on the plot correspond to the metabolic profile of the respective groups. B Hierarchical clustering of multivariate analysis of variance from PCA matrix scores. The clustering identifies whether the metabolite compositions of the various pre-treated mice groups exhibit distinctive grouping or similar patterns