Fig. 7
QHG and SM/FL decreased protein levels of HIF-1α/VEGFA/IL6 and increased expression of SLC7A11 and GPX4 proteins. ARPE-19 cells were pretreated with SM/FL or QHG for 24 h, and then the cells were further incubated with H2O2 for 6 h. Protein levels of HIF-1α (a), VEGFA (b), IL6 (c), SLC7A11 (d) and GPX4 (e) protein were detected by western blotting (f) and normalized to that of β-actin. Data are presented as the means ± SD of 3 independently repeated experiments. (* compared H2O2 group with control, # compared H2O2 with H2O2 + SM/FL, H2O2 + QHG group *, # p < 0.05; **, ## p < 0.01 ***, ### p < 0.001)