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Table 6 Effect of ALUP, BA, and LUP on KRAS, VEGF, and Cyclin D1 expression in the A549 cell line

From: A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

 

KRAS

VEGF

Cyclin D1

Control A549

1

1

1

ALUP

0.347 ± 0.02*#$

0.396 ± 0.02*#$

0.318 ± 0.02*#$

BA

0.102 ± 0.01*

0.232 ± 0.01*

0.174 ± 0.01*

LUP

0.282 ± 0.02*#

0.491 ± 0.03*#

0.544 ± 0.03*#

  1. * Significant from A549 cells (untreated) at P < 0.0001
  2. # Significant from BA treatment at P < 0.001
  3. $ Significance from LUP treatment at P < 0.01
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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