Skip to main content

Table 5 Effect of ALUP, BA, and LUP on the expression level of different markers in the A549 cell line

From: A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

 

Let-7

miRNA-21

Bax

CASP-8

CD95

Bcl-2

Control A549

1

1

1

1

1

1

ALUP

2.66 ± 0.14*#$

0.41 ± 0.02*

4.33 ± 0.22*#$

2.14 ± 0.11*#

2.65 ± 0.14*#$

0.401 ± 0.02*

BA

3.23 ± 0.17*

0.33 ± 0.01*

8.52 ± 0.43*

3.08 ± 0.16*

3.38 ± 0.17*

0.26 ± 0.01*

LUP

2.93 ± 0.15*#

0.39 ± 0.02*

5.02 ± 0.26*#

2.22 ± 0.11*#

2.08 ± 0.11*#

0.35 ± 0.02*

  1. * Significant from A549 cells (untreated) at P < 0.0001
  2. # Significant from BA treatment at P < 0.001
  3. $ Significance from LUP treatment at P < 0.01
Back to article page

BMC Complementary Medicine and Therapies

ISSN: 2662-7671

Contact us