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Table 4 Concentration of cells (ug/ml) detected at different types of apoptosis induced in A549 cells following treatment with ALUP, BA, and LUP.

From: A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

 

Total

Early

Late

Necrosis

Control A549

1.47 ± 0.08

0.37 ± 0.02

0.12 ± 0.01

0.98 ± 0.05

ALUP

16.89 ± 0.91*#$

3.76 ± 0.2*#

10.95 ± 0.59*#

2.18 ± 0.12#$

BA

25.72 ± 1.38*

2.39 ± 0.13*

15.22 ± 0.82*

8.11 ± 0.43*

LUP

19.41 ± 1.04*#

3.63 ± 0.19*

10.49 ± 0.56*#

5.29 ± 0.28*#

  1. * Significance from A549 cells (untreated) at P < 0.001
  2. # Significance from BA treatment at P < 0.05
  3. $ Significance from LUP treatment at P < 0.001
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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